Article
The role of genetic polymorphisms of angiotensin-converting enzyme in the progression of renal diseases.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 1996
McLaughlin K J, Harden P N, Ueda S, Boulton-Jones J M, Connell J M, Jardine A G
Abstract excerpt
The renin-angiotensin system is likely to be important in the progression of renal diseases because of its effect on tissue hemodynamics and glomerular cell function. Recent evidence from small studies has suggested a possible role for the genetic determinants of angiotensin converting enzyme activity in the rate of progression of renal failure. We studied the effect of the insertion/deletion (I/D) polymorphism...
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