Article
Dopamine D<sub>1</sub> and D<sub>2</sub> receptor gene expression in the striatum in Huntington's disease
1 Aug 1997
Abstract excerpt
The cellular expression of dopamine D1 and D2 receptor mRNAs was investigated in the postmortem human caudate nucleus of control cases and genetically and pathologically confirmed cases of Huntington's disease (HD) by using quantitative in situ hybridization. The HD cases were categorized (0-4) by severity of striatal neuropathology according to the Vonsattel scale. For the HD grade 0 case, a pronounced reduction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
