Article
Neurochemical characterization of dopaminergic neurons in human striatum.
Parkinsonism & related disorders - 1 Aug 2005
Cossette Martine, Lévesque Daniel, Parent André
Abstract excerpt
We examined the neurochemical phenotype of striatal neurons expressing tyrosine hydroxylase (TH) mRNA to determine if they form a distinct class of neurons within the human striatum. Double in situ hybridization (ISH) and immunohistochemical (IHC) procedures were used to know if TH mRNA-positive striatal neurons express molecular markers of mature neurons (MAP2 and NeuN), dopaminergic neurons (DAT and Nurr1) or...
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