Lack of association of catechol-O-methyltransferase (COMT) functional polymorphism in bipolar affective disorder.

doi:10.1097/00041444-199700710-00002

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Article

Lack of association of catechol-O-methyltransferase (COMT) functional polymorphism in bipolar affective disorder.

Psychiatric genetics - 1 Jan 1997

Lachman H M, Kelsoe J, Moreno L, Katz S, Papolos D F

Abstract excerpt

Abnormal catecholamine transmission has been implicated in the pathogenesis of mood disorders. Consequently, alterations in genes that are involved in catecholamine metabolism could be potential candidates for bipolar affective disorder (BPD) vulnerability. One such candidate is catechol-O-methyl...

Topics

Alleles
Bipolar Disorder
Catechol O-Methyltransferase
Catecholamines
Codon
Disease Susceptibility
Gene Frequency
Genetic Testing
Humans
New York City
Polymorphism, Genetic
White People

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