Article
Acceleration of neuronal maturation of P19 cells by increasing culture density.
Brain research. Developmental brain research - 18 Jul 1997
Parnas D, Linial M
Abstract excerpt
P19 embryonal carcinoma cells differentiate into neurons, astrocytes, and fibroblast-like cells following induction with retinoic acid. The mature neurons are capable of neurotransmitter release, and from functional synapses. We have previously shown that high culture density suppresses the cholinergic phenotype of P19 neurons. Here we demonstrate that increasing culture density accelerates the maturation of P19...
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