Article
Culture density regulates both the cholinergic phenotype and the expression of the CNTF receptor in P19 neurons.
Journal of molecular neuroscience : MN - 1 Apr 1997
Parnas D, Linial M
Abstract excerpt
The P19 embryonal carcinoma cells differentiate into neurons, astrocytes, and fibroblast-like cells following induction with retinoic acid. The cells mature into functional neurons, as determined by their ability to release neurotransmitters in a Ca(2+)- and depolarization-dependent manner. P19 neurons in culture represent a mixed population in terms of their neurotransmitter phenotype. The cholinergic phenotype...
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