Article
Culture density regulates both the cholinergic phenotype and the expression of the CNTF receptor in P19 neurons.
Journal of molecular neuroscience : MN - 1 Apr 1997
Parnas D, Linial M
Abstract excerpt
The P19 embryonal carcinoma cells differentiate into neurons, astrocytes, and fibroblast-like cells following induction with retinoic acid. The cells mature into functional neurons, as determined by their ability to release neurotransmitters in a Ca(2+)- and depolarization-dependent manner. P19 n...
Topics
- Acetylcholine
- Carcinoma, Embryonal
- Cell Communication
- Cell Count
- Cell Differentiation
- Choline O-Acetyltransferase
- Gene Expression Regulation
- Glutamic Acid
- Neurons
- Neuropeptide Y
- Phenotype
- Receptor, Ciliary Neurotrophic Factor
- Receptors, Nerve Growth Factor
- Tumor Cells, Cultured