Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups.

Human molecular genetics - 1 Aug 1997

Marron M P, Raffel L J, Garchon H J, Jacob C O, Serrano-Rios M, Martinez Larrad M T, Teng W P, Park Y, Zhang Z X, Goldstein D R, Tao Y W, Beaurain G, Bach J F, Huang H S, Luo D F, Zeidler A, Rotter J I, Yang M C, Modilevsky T, Maclaren N K, She J X

Abstract excerpt

Linkage disequilibrium (association) analysis was used to evaluate a candidate region near the CTLA4/CD28 genes using a multi-ethnic collection of families with one or more children affected by IDDM. In the data set unique to this study (Spanish, French, Mexican-American, Chinese and Korean), the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Antigens, CD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Diabetes Mellitus, Type 1

Share to Ethnicity

Share to Linkage Disequilibrium

Share to Microsatellite Repeats

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 9259273
DOI: 10.1093/hmg/6.8.1275

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9259273-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups.PMID 9259273Read ↗

CTLA4 gene polymorphisms are associated with, and linked to, insulin-dependent diabetes mellitus in a Russian population.Semantic proximity Read ↗

CTLA-4/CD 28 region polymorphisms in children from families with autoimmune hepatitis.Semantic proximity Read ↗

Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33.Semantic proximity Read ↗

IDDM12 (CTLA4) on 2q33 and IDDM13 on 2q34 in genetic susceptibility to type 1 diabetes (insulin-dependent).Semantic proximity Read ↗

Genetic susceptibility to type 1 diabetes: clinical and molecular heterogeneity of IDDM1 and IDDM12 in a german population.Semantic proximity Read ↗

Evaluation of IDDM8 susceptibility locus in a Russian simplex family data set.Semantic proximity Read ↗

A recently described polymorphism in the CD28 gene on chromosome 2q33 is not associated with susceptibility to type 1 diabetes.Semantic proximity Read ↗

CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. The Belgian Diabetes Registry.Semantic proximity Read ↗

Investigation of CTLA-4 and CD28 gene polymorphisms in patients with diabetes mellitus type 2 using PCR-RFLP in a Turkish population.Semantic proximity Read ↗

Technical note: linkage disequilibrium and disease-associated CTLA4 gene polymorphisms.Semantic proximity Read ↗

CTLA-4 49 A/G dimorphism and type 1 diabetes susceptibility: a French case-control study and segregation analysis. Evidence of a maternal effect.Semantic proximity Read ↗

The CTLA4/CD28 gene region on chromosome 2q33 confers susceptibility to celiac disease in a way possibly distinct from that of type 1 diabetes and other chronic inflammatory disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.