Article
Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33.
Diabetes - 1 Mar 2000
Marron M P, Zeidler A, Raffel L J, Eckenrode S E, Yang J J, Hopkins D I, Garchon H J, Jacob C O, Serrano-Rios M, Martinez Larrad M T, Park Y, Bach J F, Rotter J I, Yang M C, She J X
Abstract excerpt
Polymorphic markers within the CTLA4 gene on chromosome 2q33 have been shown to be associated with type 1 diabetes. Therefore, a gene responsible for the disease (IDDM12) most likely lies within a region of <1-2 cM of CTLA4. To define more precisely the IDDM12 interval, we genotyped a multiethnic...
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