Article
Evaluation of IDDM8 susceptibility locus in a Russian simplex family data set.
Journal of autoimmunity - 1 May 2005
Chistiakov Dimitry A, Seryogin Yuri A, Turakulov Rustam I, Savost'anov Kirill V, Titovich Elena V, Zilberman Lyubov' I, Kuraeva Tamara L, Dedov Ivan I, Nosikov Valery V
Abstract excerpt
Type 1 diabetes (T1D) susceptibility locus, IDDM8, has been accurately mapped to 200 kilobases at the terminal end of chromosome 6q27. This is within the region which harbours a cluster of three genes encoding proteasome subunit beta 1 (PMSB1), TATA-box binding protein (TBP) and a homologue of mouse programming cell death activator 2 (PDCD2). In this study, we evaluated whether these genes contribute to T1D...
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