Article
CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. The Belgian Diabetes Registry.
Clinical and experimental immunology - 1 Oct 1997
Van der Auwera B J, Vandewalle C L, Schuit F C, Winnock F, De Leeuw I H, Van Imschoot S, Lamberigts G, Gorus F K
Abstract excerpt
Apart from genes in the HLA complex (IDDM1) and the variable number of tandem repeats in the 5' region of the insulin gene (INS VNTR, IDDM2), several other loci have been proposed to contribute to IDDM susceptibility. Recently, linkage and association have been shown between the cytotoxic T lymph...
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