Article
Epigenetic inheritance of transcriptional silencing and switching competence in fission yeast.
Genetics - 1 Mar 1997
Thon G, Friis T
Abstract excerpt
Epigenetic events allow the inheritance of phenotypic changes that are not caused by an alteration in DNA sequence. Here we characterize an epigenetic phenomenon occurring in the mating-type region of fission yeast. Cells of fission yeast switch between the P and M mating-type by interconverting their expressed mating-type cassette between two allelic forms, mat1-P and mat1-M. The switch results from gene...
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