Article
Cell type-specific chromatin organization of the region that governs directionality of yeast mating type switching.
The EMBO journal - 16 Jul 1997
Weiss K, Simpson R T
Abstract excerpt
Switching of mating type in Saccharomyces cerevisiae is directional; MAT alpha cells recombine to transfer information from HMRa while MATa cells switch using the silent cassette at HML alpha. Genetic analysis recently has defined a 700 bp recombination enhancer approximately 29 kb from the left end of chromosome III that is necessary for directionality. The chromatin structure of this region differs strikingly...
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