Article
Selective induction of the secretion of cathepsins B and L by cytokines in synovial fibroblast-like cells.
British journal of rheumatology - 1 Jul 1997
Lemaire R, Huet G, Zerimech F, Grard G, Fontaine C, Duquesnoy B, Flipo R M
Abstract excerpt
We have investigated the potent influence of some cytokines, tumour necrosis factor-alpha (TNF-alpha), platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF) and interferon-gamma (IFN-gamma), on the secretion of cysteine proteinases (cathepsins B and L) by cultured synovial fibroblast-like cells from patients with rheumatoid arthritis (RA). After treatment of synovial fibroblast-like cells...
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