High density lipoprotein and coronary heart disease: insights from mutations leading to low high density lipoprotein.

Abstract excerpt

Hypoalphalipoproteinemia can result from defects in the genes encoding apolipoprotein A-I, the major protein component of HDL, or enzymes that are critical for the formation/maturation of mature HDL. Recent information contradicts earlier findings, suggesting that most of the affected subjects are at increased risk of developing coronary heart disease, independent of the mutated gene. A possible exception is...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Apolipoprotein A-I
• Share to Coronary Disease
• Share to Lipoprotein Lipase