Article
High density lipoproteins, reverse transport of cholesterol, and coronary artery disease. Insights from mutations.
Circulation - 1 Apr 1993
Assmann G, von Eckardstein A, Funke H
Abstract excerpt
BACKGROUND: The reverse cholesterol transport model is most widely used to explain both the role of high density lipoproteins (HDL) in lipid metabolism and the inverse association between HDL cholesterol plasma concentration and the risk for coronary artery disease (CAD). As familial HDL cholesterol deficiency is frequently paralleled with a family history of premature CAD, much interest has been directed toward...
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