Article
The genetics of high-density lipoprotein metabolism: clinical relevance for therapeutic approaches.
The American journal of cardiology - 16 Nov 2009
Strang Aart C, Hovingh G Kees, Stroes Erik S G, Kastelein John J P
Abstract excerpt
The risk for coronary artery disease (CAD) is inversely correlated with high-density lipoprotein (HDL) cholesterol plasma levels. These plasma HDL cholesterol levels are influenced by the activity of a number of enzymes and receptors, and therefore, variations in the genes encoding for these proteins may consequently result in an altered CAD risk. Identification of such pivotal players in HDL cholesterol...
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