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Article

Integrins regulate responsiveness to slit repellent signals.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 2002

Stevens Adrienne, Jacobs J Roger

Abstract excerpt

Integrins are concentrated within growth cones, but their contribution to axon extension and pathfinding is unclear. Genetic lesion of individual integrins does not stop growth cone extension or motility, but does increase axon defasciculation and axon tract displacement. In this study, we document a dosage-dependent phenotypic interaction between genes for the integrins, their ligands, and the midline growth...

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Identifiers

PMID: 12040052
PMCID: PMC6758817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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