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Article

Genes necessary for directed axonal elongation or fasciculation in C. elegans.

Neuron - 1 Feb 1992

McIntire S L, Garriga G, White J, Jacobson D, Horvitz H R

Abstract excerpt

The outgrowth of single axons through different cellular environments requires distinct sets of genes in the nematode C. elegans. Three genes are required for the pioneering circumferential outgrowth of identified motor neuron axons between the lateral hypodermal cell membrane and the basal lamina. Three other genes are required for the longitudinal outgrowth of these axons along preexisting axon bundles as well...

Topics

Animals
Axons
Caenorhabditis
Cell Movement
Fasciculation
Fluorescent Antibody Technique
Genes
Growth
Microscopy, Electron
Motor Neurons
Mutation
Nervous System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nervous System Physiological Phenomena

Source

Identifiers

PMID: 1739461
DOI: 10.1016/0896-6273(92)90297-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1739461-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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