Relationship between radiation response and p53 status in human bladder cancer cells.

doi:10.1080/095530097143491

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Article

Relationship between radiation response and p53 status in human bladder cancer cells.

International journal of radiation biology - 1 Jul 1997

Ribeiro J C, Barnetson A R, Fisher R J, Mameghan H, Russell P J

Abstract excerpt

Mutations in the p53 tumour suppressor gene are found at high frequency in bladder cancer. There is strong evidence that p53 plays an important role in controlling the cell cycle after DNA damage by ionizing radiation. However, the effect of loss of p53 function on radiosensitivity is not yet cle...

Topics

Cell Survival
Genes, p53
Humans
Immunohistochemistry
Mutation
Radiation Tolerance
Tumor Cells, Cultured
Tumor Suppressor Protein p53
Urinary Bladder Neoplasms

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