Mechanisms of retroviral mutation.

doi:10.1016/0966-842x(96)81500-9

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Article

Mechanisms of retroviral mutation.

Trends in microbiology - 1 Jan 1996

Preston B D, Dougherty J P

Abstract excerpt

Retroviruses, like other RNA viruses, mutate at very high rates (0.05-1 mutations per genome per replication cycle) and exist as complex genetically heterogeneous populations ('quasispecies') that are ever changing. De novo mutations are generated by inherently error-prone steps in the retroviral...

Topics

Animals
Genetic Variation
Humans
Mutation
RNA-Directed DNA Polymerase
Retroviridae

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