Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation.

Genes & development - 15 Jul 1997

Andersen B, Weinberg W C, Rennekampff O, McEvilly R J, Bermingham J R, Hooshmand F, Vasilyev V, Hansbrough J F, Pittelkow M R, Yuspa S H, Rosenfeld M G

Abstract excerpt

Here we report on investigation of the role of the POU domain genes Skin-1a/i (Skn-1a/i/Epoc/Oct-11) and Testes-1 (Tst-1/Oct-6/SCIP) in epidermis where proliferating basal keratinocytes withdraw from the cell cycle, migrate suprabasally, and terminally differentiate to form a multilayered, stratified epithelium. The expression of the Skn-1a/i and Tst-1 genes is linked to keratinocyte differentiation in vivo and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Genotype

Share to Membrane Proteins

Share to Repressor Proteins

Share to Transcription Factors

Source

Identifiers

PMID: 9242494
DOI: 10.1101/gad.11.14.1873

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation.PMID 9242494Read ↗

The hSkn-1a POU transcription factor enhances epidermal stratification by promoting keratinocyte proliferation.Semantic proximity Read ↗

Complex Interactions between Epidermal POU Domain and Activator Protein 1 Transcription Factors Regulate the Expression of the Profilaggrin Gene in Normal Human Epidermal KeratinocytesSemantic proximity Read ↗

2A-DUB/Mysm1 Regulates Epidermal Development in Part by Suppressing p53-Mediated Programs.Semantic proximity Read ↗

poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis.Semantic proximity Read ↗

R-spondin1 is essential in sex determination, skin differentiation and malignancy.Semantic proximity Read ↗

Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells.Semantic proximity Read ↗

RSPO1-mutated fibroblasts from non-tumoural areas of palmoplantar keratoderma display a cancer-associated phenotype.Semantic proximity Read ↗

<i>Podoplanin</i> Is a Novel Fos Target Gene in Skin CarcinogenesisSemantic proximity Read ↗

AP1 Transcription Factors in Epidermal Differentiation and Skin CancerSemantic proximity Read ↗

Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.Semantic proximity Read ↗

Pelota Regulates Epidermal Differentiation by Modulating BMP and PI3K/AKT Signaling Pathways.Semantic proximity Read ↗

p63 induces key target genes required for epidermal morphogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.