Identification of a core functional and structural domain of the v-Ski oncoprotein responsible for both transformation and myogenesis.

doi:10.1038/sj.onc.1201205

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Article

Identification of a core functional and structural domain of the v-Ski oncoprotein responsible for both transformation and myogenesis.

Oncogene - 24 Jul 1997

Zheng G, Teumer J, Colmenares C, Richmond C, Stavnezer E

Abstract excerpt

The v-ski oncogene promotes cellular transformation and myogenic differentiation. In quail embryo fibroblasts the two properties are displayed simultaneously and terminal muscle differentiation occurs only among cells already transformed by v-ski. To understand how the two phenotypes are derived...

Topics

Cell Transformation, Neoplastic
Humans
Molecular Weight
Muscles
Mutation
Protein Structure, Secondary
Retroviridae Proteins, Oncogenic
Transcription Factors

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