Article
Requirement of protein co-factor for the DNA-binding function of the human ski proto-oncogene product.
Nucleic acids research - 25 Jan 1990
Nagase T, Mizuguchi G, Nomura N, Ishizaki R, Ueno Y, Ishii S
Abstract excerpt
We identified the human c-ski gene product (c-Ski) as a protein with the apparent molecular weight of 100,000, p100c-ski, by using a c-Ski-specific polyclonal antibody. p100c-ski was a nuclear protein and p100c-ski in nuclear extracts of Molt4 cells bound to calf thymus DNA cellulose, but the bacterially synthesized c-Ski did not, suggesting that Ski was associated with another protein(s) and that the Ski complex...
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