Article
Requirement of protein co-factor for the DNA-binding function of the human ski proto-oncogene product.
Nucleic acids research - 25 Jan 1990
Nagase T, Mizuguchi G, Nomura N, Ishizaki R, Ueno Y, Ishii S
Abstract excerpt
We identified the human c-ski gene product (c-Ski) as a protein with the apparent molecular weight of 100,000, p100c-ski, by using a c-Ski-specific polyclonal antibody. p100c-ski was a nuclear protein and p100c-ski in nuclear extracts of Molt4 cells bound to calf thymus DNA cellulose, but the bac...
Topics
- Chromosome Deletion
- DNA-Binding Proteins
- Escherichia coli
- Genetic Vectors
- Humans
- Mutation
- Nuclear Proteins
- Protein Biosynthesis
- Proto-Oncogene Mas
- Proto-Oncogene Proteins
- Proto-Oncogenes
- RNA, Messenger
- Recombinant Proteins
- Restriction Mapping