Article
Genetic linkage of mild malaria to the major histocompatibility complex in Gambian children: study of affected sibling pairs.
BMJ (Clinical research ed.) - 12 Jul 1997
Jepson A, Sisay-Joof F, Banya W, Hassan-King M, Frodsham A, Bennett S, Hill A V, Whittle H
Abstract excerpt
Case-control studies have indicated that genes for the major histocompatibility complex influence the presentation and outcome of severe Plasmodium falciparum disease. To assess the role of genetic factors in mild malaria, an analysis was conducted in 217 pairs of Gambian twins (mean age, 5.3 years) concordant for this phenotype. The twins were monitored weekly during three rainy seasons (1991-93) for fever and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
