Article
Non P-glycoprotein novel proteins involved in human cancer multidrug resistance.
Bulletin du cancer - 1 Apr 1997
Baggetto L G
Abstract excerpt
Multidrug resistance of cancer cells is a serious problem in the treatment of tumors and is the leading cause of the frequent failure of chemotherapy. Cancer cell chemoresistance is based on the development of several mechanisms among which one of the most important concerns the overexpression of membrane proteins to remove cytotoxic compounds from the cytoplasm. The leading archetype of these proteins is the...
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