Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene knockouts that cause female infertility: search for novel contraceptive targets.

Frontiers in bioscience : a journal and virtual library - 1 Sept 2005

Naz Rajesh K, Rajesh Changanamkandath

Abstract excerpt

The gene knockout technology has revolutionized the fertility/infertility field. It has revealed several essential previously undiscovered molecules, new insights and novel mechanisms involved in steps of the fertility cascade in females. Using database and literature search, knockouts of at least 83 genes were discovered that demonstrated an effect on fertility of female mice. These effects ranged from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fertilization
Share to Mice
Share to Mice, Knockout

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Ovulation

Share to Reproduction

Source

Identifiers

PMID: 15970507
DOI: 10.2741/1709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene knockouts that cause female infertility: search for novel contraceptive targets.PMID 15970507Read ↗

Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated miceSemantic proximity Read ↗

Genetics of human female infertility†Semantic proximity Read ↗

Identification of zona pellucida defects revealed a novel loss-of-function mutation in ZP2 in humans and rats.Semantic proximity Read ↗

Oocyte-Specific Knockout: A Novel In Vivo Approach for Studying Gene Functions During Folliculogenesis, Oocyte Maturation, Fertilization, and Embryogenesis1Semantic proximity Read ↗

Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive TargetsSemantic proximity Read ↗

Deconstructing mammalian reproduction: using knockouts to define fertility pathwaysSemantic proximity Read ↗

Zona Pellucida Genes and Proteins: Essential Players in Mammalian Oogenesis and FertilitySemantic proximity Read ↗

CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice.Semantic proximity Read ↗

Female fertility and the zona pellucidaSemantic proximity Read ↗

Mutant <i>Zp1</i> results in Zona Pellucida Lacking and Female Infertility in Rats and HumansSemantic proximity Read ↗

The molecular genetics of the zona pellucida: mouse mutations and infertility.Semantic proximity Read ↗

Loss of Zona Pellucida Binding Proteins in the Acrosomal Matrix Disrupts Acrosome Biogenesis and Sperm MorphogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.