Rapid DNA typing for HLA-C using sequence-specific primers (PCR-SSP): identification of serological and non-serologically defined HLA-C alleles including several new alleles.

doi:10.1111/j.1399-0039.1994.tb02290.x

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Article

Rapid DNA typing for HLA-C using sequence-specific primers (PCR-SSP): identification of serological and non-serologically defined HLA-C alleles including several new alleles.

Tissue antigens - 1 Jan 1994

Bunce M, Welsh K I

Abstract excerpt

Detection of HLA-C antigens by complement mediated cytotoxicity using human alloantisera is often difficult. Between 20 to 40% of individuals in every race have undetectable HLA-C locus antigens and 9 out of the 29 sequenced HLA-C alleles so far published encode serologically undetected antigens....

Topics

Alleles
Base Sequence
DNA
HLA-C Antigens
Humans
Immune Sera
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Sequence Homology, Nucleic Acid

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