Article
Tissue-specific characteristics of cytotoxic graft-infiltrating T cells during renal allograft rejection.
Transplantation - 15 Jul 1997
Deckers J G, Boonstra J G, Van der Kooij S W, Daha M R, Van der Woude F J
Abstract excerpt
BACKGROUND: The alloresponse after renal transplantation was studied using alloreactive T cells generated in vivo (from renal biopsies) and in vitro (from mixed kidney lymphocyte cultures). METHODS: Tissue specificity of graft-infiltrating T cells (GIC) was investigated using donor-derived proxim...
Topics
- CD3 Complex
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Cell Separation
- Cells, Cultured
- Cytotoxicity Tests, Immunologic
- Epithelial Cells
- Flow Cytometry
- Graft Rejection
- Humans
- Kidney Transplantation
- Kidney Tubules, Proximal
- Phenotype
- Spleen
- T-Lymphocytes, Cytotoxic
- Transplantation, Homologous