Predominant Th1 cell infiltration in acute rejection episodes of human kidney grafts.

doi:10.1038/ki.1997.256

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Article

Predominant Th1 cell infiltration in acute rejection episodes of human kidney grafts.

Kidney international - 1 Jun 1997

D'Elios M M, Josien R, Manghetti M, Amedei A, de Carli M, Cuturi M C, Blancho G, Buzelin F, del Prete G, Soulillou J P

Abstract excerpt

T-cells and their cytokines are thought to play a major role in the genesis of cellular infiltration and rejection in human kidney allografts. Production of Th1 (IFN-gamma) and Th2-type (IL-4 and IL-5) cytokines was assessed in a large series of T-cell clones, derived from core biopsies of kidney...

Topics

Acute Disease
Cell Movement
Clone Cells
Graft Rejection
Humans
Interferon-gamma
Interleukin-4
Interleukin-5
Kidney Transplantation
Phenotype
T-Lymphocytes, Regulatory

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