Article
DNA mismatch repair in mammals: role in disease and meiosis.
Current opinion in genetics & development - 1 Jun 1997
Arnheim N, Shibata D
Abstract excerpt
The understanding of mammalian mismatch repair (MMR) gene function has been accelerated as a result of progress on several fronts. First, the biochemical analysis of MMR has been advanced by the production of purified human MMR proteins which will eventually allow reconstitution of MMR activity in vitro. Second, a wealth of clinical studies on colon cancer patients have begun to allow correlations to be made...
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