Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of hippocampal development in vivo by CR-50 mAb against reelin.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 1997

Nakajima K, Mikoshiba K, Miyata T, Kudo C, Ogawa M

Abstract excerpt

We previously generated a monoclonal alloantibody, CR-50, by immunizing reeler mutant mice with homogenates of normal embryonic brains. This antibody recently was shown to recognize a Reelin protein, which is coded by the recently identified candidate gene for the reeler mutation. However, it is still unclear whether Reelin, especially the CR-50 epitope region, is indeed responsible for the reeler phenotype in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Epitopes
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nerve Tissue Proteins

Share to Phenotype

Share to Pregnancy

Share to Serine Endopeptidases

Source

Open in PubMed Open full text

Identifiers

PMID: 9223338
DOI: 10.1073/pnas.94.15.8196
PMCID: PMC21580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of hippocampal development in vivo by CR-50 mAb against reelin.PMID 9223338Read ↗

Regulation of Purkinje cell alignment by reelin as revealed with CR-50 antibody.Semantic proximity Read ↗

The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.Semantic proximity Read ↗

Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration.Semantic proximity Read ↗

Expression of reelin in the dorsal cochlear nucleus of the mouse.Semantic proximity Read ↗

Development of commissural connections in the hippocampus of reeler mice: evidence of an inhibitory influence of Cajal-Retzius cells.Semantic proximity Read ↗

Expression of reelin, the gene responsible for the reeler mutation, in embryonic development and adulthood in the mouse.Semantic proximity Read ↗

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler.Semantic proximity Read ↗

Birthdate and cell marker analysis of scrambler: a novel mutation affecting cortical development with a reeler-like phenotype.Semantic proximity Read ↗

Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.Semantic proximity Read ↗

Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy.Semantic proximity Read ↗

Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus.Semantic proximity Read ↗

Differential effects of corticosterone on the colocalization of reelin and neuronal nitric oxide synthase in the adult hippocampus in wild type and heterozygous reeler mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.