Article
Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy.
Journal of chemical neuroanatomy - 1 Oct 2005
Miettinen Riitta, Riedel Anett, Kalesnykas Giedrius, Kettunen Hannu-Pekka, Puoliväli Jukka, Soininen Hilkka, Arendt Thomas
Abstract excerpt
Reelin, an extracellular matrix protein has an important role in the migration, correct positioning and maturation of neurons during development. Though it is generally down-regulated in the postnatal period, expression of this large glycoprotein continues in the adult brain in some cell populations. In the present study, we examined the distribution of reelin-immunoreactivity (-ir) in the hippocampal formation...
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