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Article

The hepatitis B virus X gene induces p53-mediated programmed cell death

22 Jul 1997

Abstract excerpt

The human hepatitis B virus (HBV) protein pX is a multifunctional regulatory protein that is known to affect both transcription and cell growth. Here we describe induction of apoptosis in NIH 3T3 polyclonal cell lines upon stimulation of pX expression from a dexamethasone inducible mouse mammary tumor virus (MMTV)-X expression vector. The effect of long-term pX expression on the cell survival of mouse fibroblasts...

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Identifiers

PMID: 9223332
DOI: 10.1073/pnas.94.15.8162

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The hepatitis B virus X gene induces p53-mediated programmed cell deathPMID 9223332Read ↗

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