Article
[The isolation and characteristics of mutants of the Saccharopolyspora erythraea strain resistant to thiostrepton].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Jan 1997
Nastasiak I N, Fedorenko V A, Danilenko V N
Abstract excerpt
The formation of thiostreptone resistant spontaneous and nitrosoguanidine-induced mutants in the erythromycin-producing organism Saccharopolyspora erythraea was investigated. The investigated collection of the mutants was heterogeneous by the level of the thiostreptone resistance (2.5 to 20 micrograms/ml). The thiostreptone resistance mutations had a pleiotropic effect: 17 per cent of the mutants was...
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