Article
[Isolation and characterization of Saccharopolyspora erythraea mutants, resistant to chloramphenicol].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Jan 1999
Nastasiak I N, Zavorotnaia S A, Fedorenko V A, Danilenko V N
Abstract excerpt
Formation of chloramphenicol resistant (CMr) spontaneous and nitroso-ethyl-urea-induced mutants of S.erythraea, an organism producing erythromycin, was studied. The mutants differed by the level of the chloramphenicol resistance (10 to 40 micrograms/ml). Part of the chloramphenicol resistance mutations had a pleiotropic pattern. 63.8 per cent of the CMr mutants was characterized by the growth thermosensitivity...
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