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Article

PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.

Molecular biology of the cell - 1 Dec 2006

Fujita Morihisa, Umemura Mariko, Yoko-o Takehiko, Jigami Yoshifumi

Abstract excerpt

Glycosylphoshatidylinositol (GPI) anchors are remodeled during their transport to the cell surface. Newly synthesized proteins are transferred to a GPI anchor, consisting of diacylglycerol with conventional C16 and C18 fatty acids, whereas the lipid moiety in mature GPI-anchored proteins is exchanged to either diacylglycerol containing a C26:0 fatty acid in the sn-2 position or ceramide in Saccharomyces...

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Share to Carboxylic Ester Hydrolases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum

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Source

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Identifiers

PMID: 17021251
DOI: 10.1091/mbc.e06-08-0715
PMCID: PMC1679688

Genes

GPI
PER1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.PMID 17021251Read ↗

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