Article
A role for Siamois in Spemann organizer formation.
Development (Cambridge, England) - 1 Jul 1997
Fan M J, Sokol S Y
Abstract excerpt
The vertebrate body plan is specified in the early embryo through the inductive influence of the organizer, a special region that forms on the dorsalmost side of the embryo at the beginning of gastrulation. In Xenopus, the homeobox gene Siamois is activated prior to gastrulation in the area of organizer activity and is capable of inducing a secondary body axis when ectopically expressed. To elucidate the function...
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