Article
Two modes of action by which Xenopus hairy2b establishes tissue demarcation in the Spemann-Mangold organizer.
The International journal of developmental biology - 1 Jan 2006
Murato Yasuhito, Yamaguti Mami, Katamura Miho, Cho Ken W Y, Hashimoto Chikara
Abstract excerpt
The Hairy and Enhancer-of-Split (HES) family of transcriptional repressors plays important roles in pattern formation during development throughout the animal kingdom. Generally, HES proteins repress the expression of genes specific for neighboring tissues to maintain the nature of cells expressing HES proteins, resulting in pattern formation. Xhairy2b, a Xenopus HES, establishes the prospective anterior...
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