Article
The competence of marginal zone cells to become Spemann's organizer is controlled by Xcad2.
Developmental biology - 1 Aug 2002
Levy Vered, Marom Karen, Zins Sharon, Koutsia Natalia, Yelin Ronit, Fainsod Abraham
Abstract excerpt
The organizer in vertebrate embryos is responsible for the formation of the primary body axis. In amphibian embryos, the organizer forms in the dorsal marginal zone (prospective dorsal mesoderm) at a location determined by the point of sperm entry. Using inducible versions of axis-inducing proteins, it has been shown that, irrespective of the mode of secondary axis induction, organizer formation in the ventral...
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