Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos.

Developmental cell - 1 Feb 2003

Oelgeschläger Michael, Kuroda Hiroki, Reversade Bruno, De Robertis E M

Abstract excerpt

We analyzed the Chordin requirement in Xenopus development. Targeting of both chordin Xenopus laevis pseudoalleles with morpholino antisense oligomers (Chd-MO) markedly decreased Chordin production. Embryos developed with moderately reduced dorsoanterior structures and expanded ventroposterior tissues, phenocopying the zebrafish chordino mutant. A strong requirement for Chordin in dorsal development was revealed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activins
Share to Embryonic Induction
Share to Gastrula

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lithium

Share to Morpholines

Share to Notochord

Share to Oligonucleotides, Antisense

Share to Organ Transplantation

Source

Identifiers

PMID: 12586065
DOI: 10.1016/s1534-5807(02)00404-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos.PMID 12586065Read ↗

Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b.Semantic proximity Read ↗

Nodal/Bozozok-independent induction of the dorsal organizer by zebrafish cell lines.Semantic proximity Read ↗

Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus.Semantic proximity Read ↗

Nodal signaling and the zebrafish organizer.Semantic proximity Read ↗

A zebrafish sox9 gene required for cartilage morphogenesis.Semantic proximity Read ↗

Pattern formation in zebrafish--fruitful liaisons between embryology and genetics.Semantic proximity Read ↗

Correct anteroposterior patterning of the zebrafish neurectoderm in the absence of the early dorsal organizer.Semantic proximity Read ↗

A role for Siamois in Spemann organizer formation.Semantic proximity Read ↗

Controlling morpholino experiments: don't stop making antisense.Semantic proximity Read ↗

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides.Semantic proximity Read ↗

Cooperative action of ADMP- and BMP-mediated pathways in regulating cell fates in the zebrafish gastrula.Semantic proximity Read ↗

Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.