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Article

DNA-replication checkpoint control at the Drosophila midblastula transition.

Nature - 3 Jul 1997

Sibon O C, Stevenson V A, Theurkauf W E

Abstract excerpt

Embryogenesis is typically initiated by a series of rapid mitotic divisions that are under maternal genetic control. The switch to zygotic control of embryogenesis at the midblastula transition is accompanied by significant increases in cell-cycle length and gene transcription, and changes in embryo morphology. Here we show that mutations in the grapes (grp) checkpoint 1 kinase homologue in Drosophila block the...

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Identifiers

PMID: 9214509
DOI: 10.1038/40439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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