Article
Hepatoma-derived growth factor stimulates cell growth after translocation to the nucleus by nuclear localization signals.
The Journal of biological chemistry - 22 Mar 2002
Kishima Yoshihiko, Yamamoto Hiroyasu, Izumoto Yoshitaka, Yoshida Kenya, Enomoto Hirayuki, Yamamoto Mitsunari, Kuroda Toshifumi, Ito Hiroaki, Yoshizaki Kazuyuki, Nakamura Hideji
Abstract excerpt
Hepatoma-derived growth factor (HDGF) is the original member of the HDGF family of proteins, which contains a well-conserved N-terminal amino acid sequence (homologous to the amino terminus of HDGF; hath) and nuclear localization signals (NLSs) in gene-specific regions other than the hath region. In addition to a bipartite NLS in a gene-specific region, an NLS-like sequence is also found in the hath region. In...
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