Article
Copper differentially regulates the activity and degradation of yeast Mac1 transcription factor.
The Journal of biological chemistry - 16 Jan 1998
Zhu Z, Labbé S, Peña M M, Thiele D J
Abstract excerpt
Copper is an essential metal ion that is toxic when accumulated to high intracellular concentrations. The yeast Mac1 protein is a copper-sensing transcription factor that is essential for both the activation and inactivation of genes required for high affinity copper ion transport. Here we demons...
Topics
- Alleles
- Amino Acid Sequence
- Copper
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Molecular Sequence Data
- Nuclear Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors