Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic Structure and Promoter Analysis of the Human obese Gene

1 Feb 1996

Abstract excerpt

The human gene encoding the homolog of the mouse obese (ob) gene was isolated and partially characterized. The human ob gene consists of three exons and two introns and spans about 18 kilobase pairs (kb), encoding a 3.5-kb cDNA. A 3-kb 5'-flanking region of the gene was cloned and transient transfection assay with luciferase reporter confirmed the promoter activity in differentiated F442-A adipocytes. Potential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Animal Genetics and Reproduction
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8626726
DOI: 10.1074/jbc.271.8.3971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic Structure and Promoter Analysis of the Human obese GenePMID 8626726Read ↗

Structural Organization and Chromosomal Assignment of the Human obese GeneSemantic proximity Read ↗

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.Semantic proximity Read ↗

Human Obese Gene Expression: Adipocyte-Specific Expression and Regional Differences in the Adipose TissueSemantic proximity Read ↗

The Mouse obese GeneSemantic proximity Read ↗

Overexpression of the obese (ob) gene in adipose tissue of human obese subjectsSemantic proximity Read ↗

The leptin receptor promoter controls expression of a second distinct proteinSemantic proximity Read ↗

Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha.Semantic proximity Read ↗

Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats.Semantic proximity Read ↗

Adipose tissue gene expression profiles in ob/ob mice treated with leptinSemantic proximity Read ↗

Positional cloning of the mouse obese gene and its human homologueSemantic proximity Read ↗

Positional cloning of the mouse obese gene and its human homologueSemantic proximity Read ↗

Obese (ob) gene defects are rare in human obesity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.