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Article

The Long Form of the Leptin Receptor (OB-Rb) Is Widely Expressed in the Human Brain

1 Jan 2000

Abstract excerpt

Leptin exerts important effects on the regulation of food intake and energy expenditure by acting in the brain. Leptin action is mediated by the interaction with a receptor that is alternatively spliced, resulting in at least five different isoforms. The long form (OB-Rb) has a long intracellular domain that is essential for intracellular signal transduction. The specific aim of this study was to further...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 10729790
DOI: 10.1159/000054536

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