Production and characterization of a mutant cell line defective in aminophospholipid translocase.

doi:10.1016/s0167-4889(97)00014-1

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Article

Production and characterization of a mutant cell line defective in aminophospholipid translocase.

Biochimica et biophysica acta - 5 Jun 1997

Zhao J, Sims P J, Wiedmer T

Abstract excerpt

Phospholipids are normally asymmetrically distributed between leaflets of the plasma membrane, due to the activity of aminophospholipid translocase (APT), a putative plasma membrane Mg2(+)-ATPase which is thought to selectively transport phosphatidylserine (PS) and other aminophospholipids from o...

Topics

Animals
Carrier Proteins
Cell Line
Flow Cytometry
Gene Expression
Humans
Membrane Proteins
Mice
Mutagenesis
Mutation
Phospholipid Transfer Proteins
Recombinant Proteins
Transfection

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