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Article

Production and characterization of a mutant cell line defective in aminophospholipid translocase.

Biochimica et biophysica acta - 5 Jun 1997

Zhao J, Sims P J, Wiedmer T

Abstract excerpt

Phospholipids are normally asymmetrically distributed between leaflets of the plasma membrane, due to the activity of aminophospholipid translocase (APT), a putative plasma membrane Mg2(+)-ATPase which is thought to selectively transport phosphatidylserine (PS) and other aminophospholipids from outer to inner membrane leaflet. Although several candidate proteins have been proposed to serve this function, positive...

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PMID: 9202175
DOI: 10.1016/s0167-4889(97)00014-1

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