Article
Live imaging system for visualizing nuclear pore complex (NPC) formation during interphase in mammalian cells.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jun 2010
Iino Haruki, Maeshima Kazuhiro, Nakatomi Reiko, Kose Shingo, Hashikawa Tsutomu, Tachibana Taro, Imamoto Naoko
Abstract excerpt
Nuclear pore complexes (NPCs) are 'supramolecular complexes' on the nuclear envelope assembled from multiple copies of approximately 30 different proteins called nucleoporins (Nups) that provide aqueous channels for nucleocytoplasmic transport during interphase. Although the structural aspects of NPCs have been characterized in detail, NPC formation and its regulation, especially during interphase, are poorly...
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