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Article

Dual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain association.

Journal of molecular biology - 13 Jun 1997

Li H, Lebedeva M I, Ward E S, Mariuzza R A

Abstract excerpt

The crystal structure of a mutant T cell receptor (TCR) V alpha domain containing a grafted third complementarity-determining region (CDR3) from a different V alpha was determined at 2.3 A resolution by molecular replacement using the wild-type V alpha structure as a search model. Like the wild-type V alpha domain, the mutant crystallized as a homodimer very similar to TCR V alpha V beta and antibody V(L)V(H)...

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Identifiers

PMID: 9199407
DOI: 10.1006/jmbi.1997.1047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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