Article
Association of a deletion polymorphism of the angiotensin-converting enzyme gene with left-ventricular hypertrophy in Japanese women with essential hypertension; multicenter study of 1,919 subjects.
Cardiology - 1 Jan 2000
Kimura M, Yokota M, Fujimura T, Kato S, Hirayama H, Tsunekawa A, Maeda M, Inagaki H, Ogawa S, Nakashima N, Yamada Y
Abstract excerpt
The relationship of an insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene to left-ventricular hypertrophy in individuals with essential hypertension (EH) was investigated in a large population of Japanese men and women. The ACE genotype of 762 subjects with EH (425 men and 337 women) and 1,157 healthy controls (604 men and 553 women) was determined by polymerase chain reaction...
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