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Article

Angiotensin-converting enzyme gene deletion allele increases the risk of left ventricular hypertrophy: evidence from a meta-analysis.

Molecular biology reports - 1 Dec 2012

Li Xiaobo, Li Yuqiong, Jia Nan, Guo Shujie, Chu Shaoli, Niu Wenquan

Abstract excerpt

Large panels of studies have examined the association between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and risk for left ventricular hypertrophy (LVH), yet with inconclusive results. We therefore sought to evaluate this association via a comprehensive meta-analysis. A random-effects model was applied irrespective of between-study heterogeneity. Data and study quality were...

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Source

Identifiers

PMID: 22773337
DOI: 10.1007/s11033-012-1875-6

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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